2025-01-12 04:36:52 +08:00

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R Under development (unstable) (2019-06-28 r76752) -- "Unsuffered Consequences"
Copyright (C) 2019 The R Foundation for Statistical Computing
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> # A short test on coxph.detail, to ensure that the computed hazard is
> # equal to the theoretical value
> library(survival)
> aeq <- function(a,b) all.equal(as.vector(a), as.vector(b))
>
> # taken from book4.R
> test2 <- data.frame(start=c(1, 2, 5, 2, 1, 7, 3, 4, 8, 8),
+ stop =c(2, 3, 6, 7, 8, 9, 9, 9,14,17),
+ event=c(1, 1, 1, 1, 1, 1, 1, 0, 0, 0),
+ x =c(1, 0, 0, 1, 0, 1, 1, 1, 0, 0) )
>
> byhand <- function(beta, newx=0) {
+ r <- exp(beta)
+ loglik <- 4*beta - (log(r+1) + log(r+2) + 2*log(3*r+2) + 2*log(3*r+1) +
+ log(2*r +2))
+ u <- 1/(r+1) + 1/(3*r+1) + 2*(1/(3*r+2) + 1/(2*r+2)) -
+ ( r/(r+2) +3*r/(3*r+2) + 3*r/(3*r+1))
+ imat <- r*(1/(r+1)^2 + 2/(r+2)^2 + 6/(3*r+2)^2 +
+ 6/(3*r+1)^2 + 6/(3*r+2)^2 + 4/(2*r +2)^2)
+
+ hazard <-c( 1/(r+1), 1/(r+2), 1/(3*r+2), 1/(3*r+1), 1/(3*r+1),
+ 1/(3*r+2), 1/(2*r +2) )
+
+
+ # The matrix of weights, one row per obs, one col per time
+ # deaths at 2,3,6,7,8,9
+ wtmat <- matrix(c(1,0,0,0,1, 0, 0,0,0,0,
+ 0,1,0,1,1, 0, 0,0,0,0,
+ 0,0,1,1,1, 0, 1,1,0,0,
+ 0,0,0,1,1, 0, 1,1,0,0,
+ 0,0,0,0,1, 1, 1,1,0,0,
+ 0,0,0,0,0, 1, 1,1,1,1,
+ 0,0,0,0,0,.5,.5,1,1,1), ncol=7)
+ wtmat <- diag(c(r,1,1,r,1,r,r,r,1,1)) %*% wtmat
+
+ x <- c(1,0,0,1,0,1,1,1,0,0)
+ status <- c(1,1,1,1,1,1,1,0,0,0)
+ xbar <- colSums(wtmat*x)/ colSums(wtmat)
+ n <- length(x)
+
+ # Table of sums for score and Schoenfeld resids
+ hazmat <- wtmat %*% diag(hazard) #each subject's hazard over time
+ dM <- -hazmat #Expected part
+ for (i in 1:5) dM[i,i] <- dM[i,i] +1 #observed
+ dM[6:7,6:7] <- dM[6:7,6:7] +.5 # observed
+ mart <- rowSums(dM)
+
+ # Table of sums for score and Schoenfeld resids
+ # Looks like the last table of appendix E.2.1 of the book
+ resid <- dM * outer(x, xbar, '-')
+ score <- rowSums(resid)
+ scho <- colSums(resid)
+
+ # We need to add the ties back up (they are symmetric)
+ scho[6:7] <- rep(mean(scho[6:7]), 2)
+
+ list(loglik=loglik, u=u, imat=imat, xbar=xbar, haz=hazard* exp(beta*newx),
+ mart=mart, score=score, rmat=resid,
+ scho=scho)
+ }
>
> # The actual coefficient of the fit is close to zero. Using a larger
> # number pushes the test harder, but it should still work without
> # the init and iter arguments, i.e., for any coefficient.
> fit1 <- coxph(Surv(start, stop, event) ~x, test2,init=-1, iter=0)
> temp <- coxph.detail(fit1)
> temp2 <- byhand(fit1$coef, fit1$means)
> aeq(temp$haz, c(temp2$haz[1:5], sum(temp2$haz[6:7])))
[1] TRUE
>
>
> proc.time()
user system elapsed
1.633 0.128 1.747